MEK1/2 (phospho-Ser217/Ser221) Monoclonal Antibody (7E10)

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Description Size Catalog# Price Quantity  
MEK1/2 (phospho-Ser217/Ser221) Monoclonal Antibody (7E10) 100 µg   905-652 $385.00
Background
MEK is a dual specificity kinase capable of phosphorylating both tyrosine and threonine residues. The MEK family, which is also known as MAP kinase kinase, phosphorylates MAP kinases on the conserved T-X-Y motif; phosphorylation of MAPK by MEK results in an increase in MAPK activity. MEK is involved in a diverse array of cellular processes such as stress-activated response, apoptosis, cytokine-induced cell proliferation, and DNA recombination during meiosis.

Table of Abbreviations

Applications
EIA, WB

Species Reactivity
H, M, C

Conjugate

Isotype
IgG1

Product Image(s): click to enlarge
western blot

Purification
Thiophilic adsorption and size exclusion chromatography

Immunogen
Synthetic phospho-peptide derived from the sequence of MEK 1/2, conjugated to KLH

Host
Mouse

Clone Number
7E10

Positive Control
Pervanadate-treated SW480 cells

For research use only, not for diagnostic or therapeutic use.

Documentation
Spec Sheet

Ordering Info
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