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MEKK1 Polyclonal Antibody

Brand: Stressgen Print Page
Description Size Catalog# Price Quantity  
MEKK1 Polyclonal Antibody   50 µg KAP-SA001D $135.00  
MEKK1 Polyclonal Antibody   200 µg KAP-SA001F $325.00  
Background
MEKKs (Mitogen activated protein kinase kinase kinases) are serine-threonine kinases that act as the first tier of cellular MAP kinase pathways by activation of MAP/ERK kinases, or MEKs. Many enzymes with MEKK activity have been identified, including MEKK1-4, Raf, MLK3, TAK, and DLK. MEKKs generally display little similarity outside of their catalytic kinase domains. MEKK1-4 are nearly 50% identical within their catalytic domains, and are known to regulate Erk, Jnk, and p38 MAP kinase pathways. MEKK2 and MEKK3 bind MEK5 via conserved PB1 domains, leading to downstream activation of Erk5.

Table of Abbreviations

Applications
WB

Species Reactivity
H, M, R

Isotype
not applicable

Purification
Peptide Affinity

Immunogen
Synthetic peptide derived from the sequence of mouse MEKK1, conjugated to KLH; sequence identical to human and rat.

Host
Rabbit

Clone Number
not applicable

PositiveControls
Mouse Brain Tissue Extract, LYT-MB100

For research use only, not for diagnostic or therapeutic use.

Documentation
CofA_KAP-SA001_LOT-03020913
MSDS
Spec Sheet

Product Manual

Product Name Catalog # Manual
MEKK1 Polyclonal Antibody KAP-SA001D  
MEKK1 Polyclonal Antibody KAP-SA001F  

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